It should, with careful and precise setup (all needed modules built into the kernel, everything locally compiled, USE flags for all packages carefully chosen to eliminate unnecessary dependencies), be the most targeted for the specific hardware it's running on and the specific workload it's doing—in other words, it would be carrying less cruft around. Fewer libraries to import, fewer branches to check during code execution.
In other words, execution time should be a bit better in return for spending more setup time. Benchmarks like this tend to only measure execution time.
Sounds like the next evolution of the Excel spreadsheet macro. Or maybe it's convergent evolution toward the same niche. (I still have nightmares about Excel spreadsheet macros.)