If you can show the searcher should understand the orginization of your filesystem then you can argue other places are not to be searched.
only way I can see that applying is if the warrent is about sharing files - files in a non-shared location are not part of the search. I doubt this will ever happen in the real world.
The thing about illegal searches is once they find something it is easy to put it back - then you go look for evidence and soon you have enough to get a warrant to search that. few criminals are so good at hiding their tracks that the police can't find enough evidence once they know who to look at.