The DE is the limiting factor here. MX uses XFCE, which does not yet support Wayland. For that, you'll need to use KDE Plasma or Gnome. The former requires an additional wayland session package to be installed, while Gnome comes with it by default.
You could create a new user session, install whichever one you prefer and then see if that works with Waydroid.
/shrug
I've been using it on my multiple monitor setup for well over a year with no noticeable performance impact.