I do not need anything akin to religious holyness as a basis for respecting human life. I do not want to kill them, not because their life is sacred, but because I consider myself to be a decent human being.
Some of these people are also very much sick in a medical sense. Some are unfortunately the victims of former abuse. It does not matter what you think they deserve. If you want to be a good person you should help them (as in prison with therapy), because they clearly need it and you should be someone helping people in need.
EDIT: Just as I do not believe in religion, I also do not believe in monsters.
It could very well be higher than I wrote as there is evidence of it being underdiagnosed. I just do not see why chromosomes are pertinent to discussing gender identity when I think the point is that anyone should be able to self determine whatever they want to identify as.