Man this wound me up. It's not season 11, it's season 8.
That didn't stop me downloading the wrong episode, time and time again. Same file, but it had completely the wrong name, and I need them all to say ELiTE or ETHEL consistently, otherwise it's all just wrong.
specifically for SSRIs and psychedelics
Would you group MDMA in this classification? I don't think MDMA is an SSRI.
"Psychedelic" is also a much more wide ranging classification. MDMA isn't really a psychedelic.
SSRI's directly affect the body's absorption of serotonin, meaning serotonin lingers around more. My hypothesis is that MDMA affects the release of serotonin, specifically it sustains the natural release for longer.
That's just, like, you're opinion, man.
IIRC the dude that invented MDMA never took any illegal drugs, because he always made his own, one step ahead of the legislation.
MDMA is pretty wonderful though, and I wish researchers investigated it more. I'm pretty sure it doesn't actually make you feel happy or euphoric - rather, you have serotonin and other "happy chemicals" in glands, and these glands are controlled biochemically to open and close. I think MDMA inhibits the closing mechanism.
So, if you're on MDMA, you'll basically have a normal time of it up until something makes you feel happy - the glands will open, but then the MDMA prevents them from closing, so you keep feeling that same measure of happy. If you're out in a nightclub listening to bangin music with a bunch of lasers and smoke, you're gonna have this euphoric and epic high, whereas if you're just chilling with friends in a calm house party you'll have this calm but also amplified, lovey-dovey high. MDMA isn't what makes you happy, it just lets the happy roll on. Happy happens.
This is markedly different from other drugs, which directly affect you. Nicotine makes your synapses fire faster. Opioides distract you from pain. Cocaine turns you into a coke hoarding asshole. Then, when you're off the drug you don't work properly without it. Taking more MDMA won't make you feel better again, because you've already depleted the thing that was actually making you feel good. MDMA just made you feel more good at the time.
Hell there are a bunch of receptors in the brain that are called "cannabinoid receptors", because at the time of their discovery the only thing we knew about them was that they were activated by cannabis. Since then, we've developed a slightly wider understanding of their function in the body's normal operation, and yet the name still stands.
Do we need to know how things work, when we can objectively prove that they do work?
I mean, if you go by the observations here, then basically every treatment for every syndrome should be void. In general, something is called a "syndrome" because we don't know what is wrong, we just know that something is wrong, and we know that treating it in certain ways alleviates the symptoms.
Yeah, it's the classic "more study is needed" caveat.
I'd hesitate to jump to conclusions on that. For one, the laws haven't been in effect that long.
Dr. Eric Eichenwald, a Philadelphia-based neonatologist, called the new data “disturbing,” but said experts at this point can only speculate as to why a statistic that generally has been falling for decades rose sharply in 2022.
However later on:
More than 30 states saw at least slight rises in infant mortality rates in 2022, but four states had statistically significant increases — Georgia, Iowa, Missouri and Texas.
It should be noted that, while each of these states have been trying to implement abortion bans, Iowa's ban down to 6 weeks is on hold indefinitely, so it is still legal up to 20 weeks there.
It was good for two things: on the ground news, and speaking directly to businesses to resolve customer complaints.
Is that before or after you factor in the $13 billion debt it took on to buy itself on Musk's behalf?
And then they throw a bomb in the south.
Space. Legs.
You have them. You can't really use them. Such is the way of the grind towards actual gameplay in the modern age.
Meanwhile, Futuremark had a fully 3D space FPS back in 2008, called Shattered Horizon. It never really took off, but if you imagine those duels in Ender's Game in zero G, it was like that except you could thrust in any direction. Such an untapped dimension of gameplay, up and down were all relative and you were never really safe behind cover.