TWeaK

joined 2 years ago
MODERATOR OF
[–] TWeaK@lemm.ee 2 points 2 years ago
[–] TWeaK@lemm.ee 3 points 2 years ago (2 children)

“the female brain” was from the post title, it's not what the paper says.

You said "How hard is it, especially in scientific research/publication to just say "people with higher levels of hormone A or B"? when the abstract itself said exactly that, as I quoted.

Apparently, you didn't read the article, you just came here to talk about yourself. And also to throw insults and generally be horrible.

[–] TWeaK@lemm.ee 2 points 2 years ago

Ditto! No Google needed, and Facebook apps are prohibited on my phone. I can even get banking apps working with a bit of Magisk, working in Zygisk domain with a deny list hiding it from the apps. Apparently proper SafetyNet checks aren't that common anymore.

For browsers, I'd recommend Mull and Mulch. Mull is a privacy fork of Firefox, Mulch is a hardened version of Android System Webview (the backend browser that lots of apps use). Both come pre-installed with DivestOS.

[–] TWeaK@lemm.ee 3 points 2 years ago* (last edited 2 years ago) (1 children)

So trans men on hormones would be more sensitive to anesthesia and trans women on HRT would be less sensitive to anesthesia. Also cis women with PCOS would be more susceptible to anesthesia.

Trans men on testosterone, yes; cis women with PCOS, yes (provided their testosterone level isn't reduced through treatment); trans women on HRT - maybe.

It's about levels of testosterone, so any woman (trans or otherwise) with high levels of testosterone would be more sensitive. If a trans woman on HRT (estrogen) still had a relatively high level of testosterone then she would still be sensitive to anesthetic.

It's not really got anything to do with levels of estrogen. In fact, it mentions that removal of female sex organs (oophorectomy) has no effect. However, it does mention "Conversion of testosterone to estradiol [a form of estrogen] by aromatase is partially responsible for this effect." which, I'll be honest, is beyond my understanding of how hormones work in the body (gonna have to dig in and read the cited sources). It does not seem that estrogen pathways have this effect, rather it's testosterone in its normal, uninhibited biochemical pathways that does it - inhibiting aromatase lowers sensitivity, in spite of higher testosterone levels.

[–] TWeaK@lemm.ee 1 points 2 years ago

it’s Apple the one they should complain to.

Or walk away from.

[–] TWeaK@lemm.ee 6 points 2 years ago* (last edited 2 years ago) (6 children)

The abstract literally says that. "Anesthetic sensitivity is bidirectionally modulated by testosterone."

Why is it so important that this article be about you and trans issues? You come across as quite conceited.

Trans matters are only very tangentially related here. This is about testosterone and anesthetic sensitivity. It suggests one of two things:

  1. We should be modulating anesthetic dosage by a person's testosterone level.
  2. We should be giving some people testosterone injections alongside anesthetic such that their testosterone level meets that which the anesthetic dosage is set to.
[–] TWeaK@lemm.ee 2 points 2 years ago

Lol that's basically the Brave attitude, drown out the controversy with a marketing campaign and pull in more new unsuspecting users than the ones you lose.

[–] TWeaK@lemm.ee 2 points 2 years ago (2 children)

Android was a victim of the NSO's Pegasus because of WhatsApp, and possibly that only worked because Facebook negotiated with phone manufacturers to bundle dodgy pre-installed system apps outside the Google Play Store.

Apple's iOS was a victim of the NSO's Pegasus because of iMessages.

For me, that's enough to completely steer clear of iOS altogether. I mean, the lack of customisation and control over my device was already enough, but that kind of vindicated it for me.

[–] TWeaK@lemm.ee 1 points 2 years ago (1 children)

Lol for a moment there I thought I was going off the rails with my puffa jacket rant above, but your segway into "free market feefees" is far more unhinged.

[–] TWeaK@lemm.ee 0 points 2 years ago (2 children)

"My actions mean nothing because everyone else won't do it" is exactly what everyone else is thinking.

You're making excuses. Be the change you know should happen. Don't be a sheep.

Don't buy puffa jackets. Seriously. They're fucking everywhere now. Don't do it, you don't need it, they're cheap and overpriced.

[–] TWeaK@lemm.ee 4 points 2 years ago

I like to view things with quantum physics in mind. "That's weird and counter-intuitive...", "I guess it's meant to be that way."

Obviously it doesn't apply to everything, and often your gut feeling is probably right. But the philosophy helps in keeping an open mind.

With trigonometry, you don't use it directly, but AC electricity and radio waves (eg WiFi or your phone) extensively rely on it.

[–] TWeaK@lemm.ee 10 points 2 years ago (1 children)

You're literally using a device powered by electricity that extensively relies on an understanding, implementation and exploitation of sinusoidal maths.

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