So, after taking some time to digest this information, I have a couple of follow-up questions, if you don't mind answering them.
First of all, where do things stand with drugs? Is it just not something academics are working on, but presumably being done (or already finished) within proprietary institutions (e.g. Big Pharma)? Can you point me to some recent papers on the subject?
~~Secondly, what about enzymes? Binding proteins are interesting, certainly, but it's enzymes that really excite me the most. Is anyone working on custom enzyme design, and if so, can you link some papers on that?~~ In looking more closely at that Nature paper, I see that enzymes are something of a work-in-progress as yet. If you have anything else on the subject, I'd welcome that, but if there's nothing else of note there, that's fine.
Thank you for mentioning this to begin with, by the way, I really appreciate the info you've already shared!
This is great information, thank you so much!