Right now a bunch of countries have operational nuclear weapons (and this ends in 1998). No one has used one in warfare since 1945 - right now there's basically a fragile truce on nuclear war. Putin threatened to use one but even he didn't actually pull that trigger.
If someone does... then I expect everyone does.

It's too early to have much data, but there is some evidence that GLP-1 blockers are exacerbating eating disorders like anorexia:
https://shmabstracts.org/abstract/glp-1-induced-anorexia-what-to-do-when-the-medicine-works-too-well/
Which makes sense - the drugs make you feel like you don't need to eat, so you don't eat. If you were already not eating enough, it amplifies that.