About 20 years ago I read a grim book about plane crashes. They claimed that the number 1 predictor of crash survivability on commercial craft was being a male between the ages of 20 and 50. They're apparently much better equipped to claw and climb over the other passengers on the way out.
Grim. I fly a lot and think about it at least every other trip.
I'm sensitive to noise, and usually book late enough that the only seats available are in back. And fly at least once a month.
Absolutely decent noise cancelling headphones are available for under $70 US last time I bought some. Mine were called Q30 or something, and they were better than my Sennheisers from 2016-ish. Worth every bit. If one can afford a ticket, one can afford this one thing to make it less awful.