this post was submitted on 05 Dec 2023
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Vaccines can be delivered through the skin using ultrasound. This method doesn’t damage the skin and eliminates the need for painful needles. To create a needle-free vaccine, Darcy Dunn-Lawless at the University of Oxford and his colleagues mixed vaccine molecules with tiny, cup-shaped proteins. They then applied liquid mixture to the skin of mice and exposed it to ultrasound – like that used for sonograms – for about a minute and a half.

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[–] Gigan@lemmy.world 3 points 2 years ago (1 children)

This is more unsettling than a needle to me.

[–] deranger@lemmy.world 2 points 2 years ago* (last edited 2 years ago) (3 children)

What do you think about jet injectors?

a narrow, high-pressure stream of liquid penetrates the outermost layer of the skin to deliver medication to targeted underlying tissues

https://en.wikipedia.org/wiki/Jet_injector

[–] takeda@lemmy.world 2 points 2 years ago (4 children)

This is what I was thinking when reading the title. That one supposedly was cool, because there was no needle, never seen one in action but I presume there also was no bleeding.

Yet we don't see them used today, apparently the biggest reason was that there was a splashback and retrograde follow and then patient's blood could end up contaminating the nozzle, so basically it was like using the same needle on multiple patients.

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[–] Neato@kbin.social 2 points 2 years ago

It's how I got some vaccines in gradeschool. To the underside of my upper arm, the fatty bit. Hurt like fuck.

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[–] theodewere@kbin.social 2 points 2 years ago (2 children)

man a little vaccine needle is the least painful shot, i didn't even feel the last 5 i got until the next day

[–] Maeve@kbin.social 1 points 2 years ago

Intramuscular always caused me soreness, except maybe once. I don’t know what that nurse did differently, I felt the needle sink in, and it hurt; but there was near-zero residual soreness.

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