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A protein called neurofilament light chain (NfL)—studied in humans in the context of neurodegenerative diseases and aging—is also detectable in the blood of numerous animals, and NfL levels increase with age in mice, cats, dogs and horses. Experts from the DZNE and the Hertie Institute for Clinical Brain Research (HIH) at the University of Tübingen report these findings in PLOS Biology. In their view, this biomarker could help to assess the biological age of animals and estimate their life expectancy.

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