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The nuclear envelope (NE) is a dynamic and selective barrier that organizes genome function and nucleocytoplasmic communication, and its structural deterioration is a hallmark of aging associated with diverse human diseases. Now, researchers from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences (CAS) have uncovered a previously unrecognized mechanism by which mitochondrial redox signaling preserves the NE structure and delays aging.

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