this post was submitted on 27 Jan 2026
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In our latest attempts to make lab rats immortal, a new compound has been shown to reverse late stage Alzheimer's disease in lab mice. This is a rare case where the title isn't even clickbait.

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[–] Honytawk@feddit.nl 8 points 7 hours ago

Where is that comic about reporters creating misinformed headlines about science?

[–] hector@lemmy.today 10 points 11 hours ago

Odds are it is at least somewhat bullshit, oversold, to garner more funding.

[–] Trilogy3452@lemmy.world 45 points 19 hours ago (1 children)

An unforgettable moment for those mice

[–] krimson@lemmy.world 3 points 12 hours ago

Underrated comment.

Oh, yeah? How come they still cant tell us how fucking magnets work?

Eat shit, "science."

[–] gibmiser@lemmy.world 69 points 1 day ago (3 children)

In a mouse model. The mice don't have alzheimers they have... something we gave them that looks like it... Hopefully it is similar enough

[–] DrBob@lemmy.ca 11 points 1 day ago (1 children)

We did something to the mice then rescued it in a different way. Hooray! Next we'll save test tubes from cancer...again.

[–] scarabic@lemmy.world 28 points 22 hours ago (1 children)

If you can’t get excited by incremental advancements, you should probably unsubscribe from science as a topic.

[–] DrBob@lemmy.ca 18 points 17 hours ago (1 children)

Dude it's worse than that. I was a working neuroscientist for almost twenty years. So...jaded.

[–] scarabic@lemmy.world 5 points 15 hours ago

This is why almost everyone does development, not research.

[–] SaveTheTuaHawk@lemmy.ca 5 points 23 hours ago* (last edited 3 hours ago) (2 children)

There has been a fucking epidemic of MD/scientists running to the media with miracle cures lately.

Mice do not get Alzheimers, they were engineered to show one aspect of the disease that has been promoted by fraudulent studies. As for the reversal, mouse brains are highly plastic and similar to a human baby, nothing like a >60 year old.

[–] OrteilGenou@lemmy.world 1 points 22 minutes ago

HAH HEY EVERYONE THIS GUY THINKS MICE HAVE BRAINS MADE OF PLASTIC /s

[–] LifeInMultipleChoice@lemmy.world 6 points 22 hours ago

Well I hear we are adding more plastic to the brain through micro dosing micro plastics in our every day lives. Wait...

[–] piconaut@lemmy.ca 5 points 1 day ago (1 children)

Yeah, I didn't read the whole thing but apparently only in 5xFAD mice. I wish they would have also tried it in a Tau model like PS19.

[–] SaveTheTuaHawk@lemmy.ca 2 points 3 hours ago

Both pointless. Mice do not get neuronal loss like human disease. These diseases have been stalled for 30 years on animal models generating "high impact" manuscripts that go nowhere.

Meanwhile, in human research, just taking vaccines can lower AD incidence by 30%. For real, proven. Not "soon", not "within 5 years" . That is far mor relevant than animal model studies.

[–] bizarroland@lemmy.world 21 points 1 day ago (1 children)

Mouse grandpa: John?

Mouse Grandson: Grampa, you remember me?

Mouse grandpa: Yes, I remember. It's all coming back now. You ate my cheese and fucked my wife you piece of shit!

Sounds of mouse battle reverberating

[–] KneeTitts@lemmy.world 9 points 22 hours ago (2 children)

I believe this population of super-mice we are making that are immune to all disease will be the dominant life form on earth after we have extincted ourselves. Im in favor of this future.

[–] Zorque@lemmy.world 6 points 22 hours ago
[–] altphoto@lemmy.today 1 points 22 hours ago

They will do our bidding in forever thanks to us.

[–] halfsalesman@piefed.social 10 points 23 hours ago (2 children)

Scientific advancements often seem like the only good news we ever seem to get.

[–] hector@lemmy.today 1 points 11 hours ago

Any drug would cost 20 million a course. Not even exagerating there either. A new one is doing dynamic pricing, charging some as much as 3 million and others over 1 million for a course. For drugs developed with goddamned charity money.

[–] user224@lemmy.sdf.org 6 points 23 hours ago (1 children)

Don't worry, they'll get monetized to hell.

[–] InabaResident@feddit.org 0 points 17 hours ago

While often true, they still end up making life better for millions of people often enough to be worth it.

[–] HeyThisIsntTheYMCA@lemmy.world 3 points 19 hours ago

it's lab mice. it's NAD+. i can't remember because i'm not an ad researcher, but there are 3 models of AD. one is NAD+, two aren't. Most of the research was going into NAD+ or another, and they discovered that that specific model was not going to help human patients. It did nothing to effect research or funding. that was about... 15 years ago? so forgive me if i don't get up.

[–] Sirdubdee@piefed.social 4 points 23 hours ago

Now we work towards changing elderly people into mice to cure their Alzheimer’s!

[–] AmidFuror@fedia.io 4 points 1 day ago

Let's see if it works for Charlie now.

[–] PushButton@lemmy.world 0 points 23 hours ago

Aahh, those lucky mice. Yet another cure for Alzheimer, without counting the multiple cancer miracle-like cures.

Any news for human yet?

[–] the_q@lemmy.zip -4 points 23 hours ago (2 children)

I hate how we treat animals for the benefit of an objectively worse animal.

[–] communist@lemmy.frozeninferno.xyz 0 points 12 hours ago* (last edited 12 hours ago) (2 children)

Curing disease is undoubtedly worth animal suffering. Once the disease is cured the benefits will confer to all future humans until we go extinct, I am certain if you were suffering from alzheimers you'd be of a different opinion.

point these criticisms at the cosmetics industry.

[–] the_q@lemmy.zip 1 points 5 hours ago (1 children)

I don't value the human experience like you do. Humans should die and suffer like any other animal. We're able to choose to do good and yet still inflict suffering for convenience. Instead of correcting systemic issues that cause increases in disease we inflict suffering on innocent animals in an attempt to provide a band aid that's often behind a paywall.

[–] communist@lemmy.frozeninferno.xyz 1 points 4 hours ago (1 children)

would you tell your spouse that after their diagnosis?

cartoonish evil.

[–] the_q@lemmy.zip 1 points 49 minutes ago

My spouse died in a house fire less than 2 years ago with my father in law, 2 cats, a dog and a life time of things. I walked out of the fire and heard her scream. What animal experiment helped her?

[–] hector@lemmy.today 1 points 11 hours ago (2 children)

You are not including the US in humanity clearly, because few can afford this kind of drug here.

[–] boonhet@sopuli.xyz 2 points 8 hours ago

Yea but the rest of us will still benefit. The US is like 5% of the world's population, give or take. Okay there's other countries with shitty health care systems (developing ones where they just haven't gotten there yet), but I'd reckon like 80% of the world's population would have easy and cheap or free access to it through government funded healthcare, or at least a better private system than the US. That's still a net good. Y'all just need to get your shit in order, but unfortunately at this point it's going to be harder and harder to do it without violence.

[–] communist@lemmy.frozeninferno.xyz 2 points 9 hours ago* (last edited 9 hours ago) (1 children)

The existence of such a drug benefits humanity even if the USes barbaric policies prevent adoption.

furthermore even if nobody in the US got it ever it would still help an unimaginable number of people

what is the logic here? Don't help medicine move along because of one crazy country?

[–] hector@lemmy.today 1 points 9 hours ago* (last edited 9 hours ago) (1 children)

Advancements are only for the rich in these lands. Far from still being for the benefit, prolonging the rich's lives is arguably not.

It would be an advancement if the rights to the drug were owned by some sort of benefit corporation, or non profit, or were not sold to the worst people in the world.

It's not though. They are maximizing revenue with no one in government to stop them, to call them on gouging.

i'm a communist you're barking up the wrong tree

[–] TheLeadenSea@sh.itjust.works 2 points 20 hours ago

All value judgements are subjective. "Better" and "worse" are value judgements, not statements about reality, so they cannot be objective. But subjectively I agree with you that we treat animals awfully, not even mainly in science experiments - at least they have a tangible benefit. Just look at the way animals are bred to be tortured and murdered in factory farms.