I can’t get the Windows based firmware updaters for my motorcycle helmet Bluetooth headset and joystick fully running under Wine/Lutris/Whatever. They both use USB and just will not connect.
Also, once a quarter I have to use an archaic Excel sheet that is heavily dependent on some VB Script. This file absolutely will not open correctly in anything other than a locally installed version of Excel because the script needs a real local printer and Open/Libre/Whatever cannot handle the insanity of the VB Script. I have a Windows VM just for this one thing.