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Tightening the focus of subcellular snapshots: Combined approach yields better cell slices for cryoET imaging (phys.org)

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Taking images of tiny structures within cells is tricky business. One technique, cryogenic electron tomography (cryoET), shoots electrons through a frozen sample. The images formed by the electrons that emerge allow researchers to reconstruct the internal architecture of a cell in 3D with near-atomic resolution.

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