this post was submitted on 22 Sep 2025
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Officials will also tout the drug leucovorin as a potential autism treatment, in what President Donald Trump has billed as a “very important” announcement.

Access options:

I've got no idea what the alleged evidence for this is, but what I do know is that the people making these announcements are completely untrustworthy.

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[–] RedWeasel@lemmy.world 71 points 3 days ago (1 children)

what I do know is that the people making these announcements are completely untrustworthy

You are being overly kind. These people are BATSHIT Crazy.

[–] watson387@sopuli.xyz 38 points 3 days ago (2 children)

I'd say they're moronic evil.

[–] monotremata@lemmy.ca 19 points 3 days ago (1 children)

This suggests a whole new kind of D&D alignment chart.

[–] idealotus@lemmy.world 9 points 3 days ago (1 children)

I'd say they're chaotic evil with 0 INT. I'm not even sure where they put their points.

[–] SpikesOtherDog@ani.social 3 points 3 days ago

Charisma, I guess.

[–] RedWeasel@lemmy.world 15 points 3 days ago (1 children)

I feel 'evil' requires a knowledge that what they is doing is wrong with intent in doing so. I don't think RFKjr is sane enough to know he is being harmful unfortunately. The administration is filled to the brim with both, people being harmful intentionally and ignorantly.

RFK is a crunchy parenting facebook group that has somehow achieved sentience.

[–] joyjoy@lemmy.zip 10 points 2 days ago

For all the reasons Tylenol should be pulled from shelves, autism probably isn't one of them.

[–] oxysis@lemmy.blahaj.zone 15 points 3 days ago (1 children)

I’m very happy I didn’t get diagnosed when I was younger, it’s sad though that I have to make the choice to not get diagnosed to not have to worry as much

Same here. I have never been diagnosed with anything mentally related thankfully.

[–] Jaysyn@lemmy.world 14 points 3 days ago* (last edited 2 days ago) (3 children)

Weird how the famously autistic Temple Grandin had been alive for 8 years when Tylenol went on the market.

-EDIT-

Also:

https://jamanetwork.com/journals/jama/fullarticle/2817406

Findings In this population-based study, models without sibling controls identified marginally increased risks of autism and attention-deficit/hyperactivity disorder (ADHD) associated with acetaminophen use during pregnancy. However, analyses of matched full sibling pairs found no evidence of increased risk of autism (hazard ratio, 0.98), ADHD (hazard ratio, 0.98), or intellectual disability (hazard ratio, 1.01) associated with acetaminophen use.

[–] ripcord@lemmy.world 4 points 3 days ago (1 children)

I don't know the background for the bullshit here, but I really doubt anyone is implying that it is the ONLY cause.

[–] Jaysyn@lemmy.world 7 points 3 days ago

Giving fascists the benefit of the doubt is a stupid move.

[–] partial_accumen@lemmy.world 3 points 3 days ago

That is easily explained. Temple Grandin's parents were time travelers from the future where Tylenol existed, making Temple also a time traveler as a baby to have a birthdate recorded 8 years prior to Tylenol's release to the market. /s

[–] Salsa_Shark@scribe.disroot.org 1 points 2 days ago* (last edited 2 days ago)

Weird how the famously autistic Temple Grandin had been alive for 8 years when Tylenol went on the market.

Acetaminophen has been out since the mid/late 1800's.

[–] unrealizedrealities@kbin.melroy.org 21 points 3 days ago (3 children)

Fabulous! Now treat those with autism with respect and dignity........................

[–] IndridCold@lemmy.ca 4 points 3 days ago

I think this is a lead up to rounding up everyone with autism and moving them to special camps for "education".

Best I can do is arrest all the parents who gave their kids Tylenol for neglect and put them in camps.

And the kids too. Oh and we can give them all free jobs while they are there to give them the opportunity for them to learn new trades.

These non-human second rate child abusers need to be separated from us, they were attacking the children!

[–] gnate@lemmy.world 2 points 3 days ago

Starting with eliminating these bullshit claims for "causes" of autism.

[–] snausagesinablanket@lemmy.world 16 points 3 days ago (1 children)
[–] Ulvain@sh.itjust.works 10 points 3 days ago (1 children)

Thank you for sharing! Saving a click: So there was a first, flawed study, which studied the link between Tylenol and autism on the basis of correlation (not causality), and they failed to factor in other underlying reasons why parents who end up having an autistic child might use acetaminophen slightly more often (ex: the parents themselves have a condition that makes them take Tylenol more often). The new thorough study clearly demonstrates that there are no links.

[–] SaveTheTuaHawk@lemmy.ca 7 points 3 days ago

The experiments that proves no connection between Tylenol and autism has been done two ways:

  1. In the 80s there was a tainted Tylenol scandal and sales were suspended and all pills recalled. Sales dipped to near zero for years. No difference to autism rates.

  2. Many countries avoid Tylenol use due to liver toxicity. No difference in autism rates.

[–] resipsaloquitur@lemmy.world 14 points 3 days ago

Is this butterfly an autism?

[–] AlecSadler@lemmy.blahaj.zone 7 points 3 days ago

McNeil Consumer Healthcare must not have paid their bribe money.

[–] foggy@lemmy.world 6 points 3 days ago (5 children)

Look, acetaminophen is one of the most harmful OTC drug without this nonsese.

If they stop here, fine. But fight it like hell.

[–] CatDogL0ver@lemmy.world 7 points 3 days ago (1 children)

Alcohol is worse. Why is no on banning it?

If you take too much of something, it becomes harmful. What an epiphany.

[–] LifeInMultipleChoice@lemmy.world 2 points 3 days ago* (last edited 2 days ago) (1 children)

I mean the sheer amount of sugar in our food has to be the largest cost to lifespans/healthcare in the U.S.

Id like to see us make a change over time introducing not bans but better ways to regulate packaging.

I don't want it to have warnings everywhere and dead fetuses and shit, I just want things like, green boxes, blue boxes, magenta boxes, stuff like that. Maybe an easy to see letter in the lower left for those who are color blind

[–] CatDogL0ver@lemmy.world 1 points 17 hours ago (1 children)

What dead foetuses? Paracetamol doesn't do that.

[–] LifeInMultipleChoice@lemmy.world 1 points 16 hours ago* (last edited 16 hours ago)

I was talking about boxes/cans for food, like say ramen, cheese it's, swiss cake rolls, green beans what have you.

The dead fetuses is a reference to the way countries have tried to use scare tactics on products to get them not to use a product. Like cigarettes. I don't want them to do that shit with food as well, but bad diets, such as added high fructose corn syrups and what not I was advocating for foods having main colors for boxes and maybe a letter on the can for colorblind people. That says to a purchaser who isn't going to read, this soup isn't as bad for me as this other soup. Or when buying snacks for their kids they know are going to sneak them, they can buy snacks/chips etc that are better or worse intentionally with little effort. Bad diets have been and will always be the #1 highest cost to a countries healthcare and leading the natural early death rates.

Example of what I don't want:

[–] voracitude@lemmy.world 15 points 3 days ago (9 children)

Source please? I haven't been able to find anything credible about whatever danger it is you're referencing - unless the danger is overdosing because the person didn't know they were taking acetaminophen in different forms? If the danger is people not bothering to check what they're ingesting, I'll concede that's a clear and ever-present danger - just not one specific to acetaminophen.

[–] Mouselemming@sh.itjust.works 6 points 3 days ago* (last edited 3 days ago) (2 children)

I think the reason people overdose on Tylenol, and often don't realize that's the problem until their liver is failing, is that for decades Tylenol was presented as the "safe" choice for fever and pain control. Which really just means it's not going to give little kids Reye Syndrome. But because you've absorbed that idea as a little kid, you're not looking for danger unless you specifically re-learn about overdose hazard. And too many people don't, because shitty education. Then you add all the mixed "cold and flu" OTC medications with the ingredients in tiny print, and the fact that by the time you have uncomfortable symptoms it's probably too late to pump your stomach, so people die. And that's without counting in the little ones who got into the grape chewables or drank the whole bottle of the baby's bubblegum liquid.

Editing to add: In my experience, Tylenol just doesn't do a very good job of easing pain, which might also lead to overdose. It never worked for my severe period cramps, which Advil did. And there's a case of a man dying because he took 5 extra-strength every hour trying to control his dental pain, which I would never do but I can affirm it doesn't do shit for toothache either.

But autism? Nah.

[–] I_Has_A_Hat@lemmy.world 3 points 3 days ago (3 children)

A combination of ibuprofen and acetaminophen (paracetamol) is a crazy effective painkiller. It's been found to be even more effective than some opioids. Watch your dosage, know what you're taking, and it's perfectly safe.

[–] Mouselemming@sh.itjust.works 1 points 2 days ago

If you do that, be sure to space them out, alternating, with at least a couple of hours between. Having done it on doctor's advice, I've noticed the Tylenol is barely enough to keep me hanging on as the previous Advil wears off and until I can take the next one. I'm not 💯% sure it was helping at all, but at least I could say to myself, "surely it will be kicking in any moment now..." until I got through to where I could start saying "Only half an hour more until you can take the good stuff."

I think people have idiosyncratic responses to pain meds. I don't respond to Aleve either. Aspirin is mildly helpful. But a single Motrin was all I needed the day after a C-section.

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[–] voracitude@lemmy.world 1 points 3 days ago (1 children)

but autism? Nah.

Preaching to the choir haha.

Regarding your point on the efficacy of acetaminophen: agreed wholeheartedly. Like /u/i_has_a_hat said, if you combine it with ibuprofen it's far more effective. My go-to for bad pain is 500-1000mg acetaminophen and 400mg ibuprofen; I stole the idea from my ex's neurologist when he prescribed it for dealing with the side effects of her main medication (and he also specifically said it would help with her period cramps too, hers were always bad).

As to the guy taking 5 an hour... That's an incredible amount of acetaminophen, even "normal strength". You said you wouldn't, I think I couldn't take that many pills. Just the idea has me gagging 🤢 I think it's fair to call that one an outlier in the data.

[–] Mouselemming@sh.itjust.works 2 points 2 days ago

My doctors have said to take them alternating, not at the same time, and it has worked to smooth out the waves a bit although I'm definitely aware of the difference in effectiveness.

And yes, that dude must have been crazy, badly misunderstood directions, or just in such agonizing pain he didn't care he was killing himself. Sadly, liver failure is also a painful way to go.

[–] paraphrand@lemmy.world 2 points 3 days ago

Yeah, it’s easy to take too much.

[–] foggy@lemmy.world 2 points 3 days ago* (last edited 3 days ago) (2 children)
[–] Batman@lemmy.world 9 points 3 days ago

The dosage they describe as overdosing in adults is 24x that of a high strength recommended dosage. That does not seem "easy" to OD.

[–] voracitude@lemmy.world 3 points 3 days ago* (last edited 3 days ago) (3 children)

I appreciate the sources, but I don't appreciate the

You... you didn't try at all, did you?

Because nothing you've posted here is news to me. I think you'll find I said:

If the danger is people not bothering to check what they're ingesting, I'll concede that's a clear and ever-present danger - just not one specific to acetaminophen.

So I'll just quote directly from your very first link, because the rest of them don't say anything different:

Responsible for 56,000 emergency department visits and 2600 hospitalizations, acetaminophen poisoning causes 500 deaths annually in the United States. Notably, around 50% of these poisonings are unintentional, often resulting from patients misinterpreting dosing instructions or unknowingly consuming multiple acetaminophen-containing products.

And

At therapeutic levels, acetaminophen is generally considered safe. However, instances of acetaminophen toxicity often arise due to patient misconceptions about dosing or a lack of awareness regarding its presence in multiple medications they may be consuming. Intentional ingestion of large doses also contributes to toxicity.

So, in around 50% of cases, the danger is people not bothering to check what they're ingesting. They took other medications containing acetaminophen and didn't know it, or they took other drugs that amplified the ability of the acetaminophen to cause damage (like alcohol, which is made very clear you're not supposed to take with acetaminophen).

In the rest, overdoses were intentionally taken, so you can't really count those in the danger statistics since the goal was to use it dangerously.

To put this in perspective:

When taken at therapeutic doses, acetaminophen has a good safety profile. The therapeutic doses are:

  • 10 to 15 mg/kg/dose in children every 4 to 6 hours with a maximum dose of 80 mg/kg/d
  • 325 to 1000 mg/dose in adults every 4 to 6 hours, with a maximum daily dose of 4 g/d

Toxicity is likely to develop in adults at:

  • >12 g over a 24 hours
  • 7.5 to 10 g in a single dose
  • Doses >350mg/kg

Toxicity in children occurs following a single dose of 150 mg/kg or 200 mg/kg in otherwise healthy children aged 1 to 6.

Just do the maths on how much acetaminophen you normally take for any given ailment, and you'll realise just how far beyond those doses the danger really lies (or maybe that you're one of the people who doesn't check what they're taking).

So, to conclude: acetaminophen is indeed dangerous if you don't pay attention to what you're taking or how much. Other examples of things that are dangerous if you don't use them right: cars, ovens, lawnmowers, cotton buds, the internet... the full list is quite long, actually, but I'm sure you get the idea.

[–] ripcord@lemmy.world 1 points 3 days ago (1 children)
[–] voracitude@lemmy.world 1 points 2 days ago (1 children)
[–] ripcord@lemmy.world 1 points 2 days ago

What a tool.

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[–] xyzzy@lemmy.today 12 points 3 days ago (1 children)

My ex's cousin died from renal failure from Tylenol.

All painkillers have downsides. Ibuprofen triples the risk of stroke—more with greater dosages. But claiming Tylenol causes autism is stupid.

[–] PlantDadManGuy@lemmy.world 4 points 3 days ago (1 children)

Tylenol is not nephrotoxic. It's metabolized by the liver, and it can absolutely cause damage in high doses, but I think your statement is in error.

[–] xyzzy@lemmy.today 1 points 2 days ago* (last edited 2 days ago)

Conclusion

Acetaminophen is associated with a significantly increased risk of newly developing renal impairment in adults. Physicians who prescribe acetaminophen should be aware of potential adverse renal effects. A longitudinal study that further explores this association is warranted.

https://pmc.ncbi.nlm.nih.gov/articles/PMC7105620/

It's also worth noting that it's pretty much the only OTC painkiller you're allowed to take while pregnant, so

A. I would imagine the percentage of people who've taken it at least once while pregnant is staggeringly high, to such a point that this would be very difficult to adequately establish causation and

B. They are, once again, just screwing over pregnant people

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