I guess Barbara was the inspiration for the Snickers ad.

Quark: Let me tell you something about Humans, Nephew. They’re a wonderful, friendly people, as long as their bellies are full and their holo-suites are working. But take away their creature comforts, deprive them of food, sleep, sonic showers, put their lives in jeopardy over an extended period of time and those same friendly, intelligent, wonderful people… will become as nasty and as violent as the most bloodthirsty Klingon. You don’t believe me? Look at those faces. Look in their eyes.