this post was submitted on 21 Mar 2026
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This sounds like there's a hardware problem with either the motherboard or CPU, or possibly the power supply. What motherboard model do you have? Is it one of the Asus models with a backup UEFI/BIOS storage? Does it have one of those 2-digit error code displays?
Is the failure with USB peripherals true for both the fixed USB ports on the back and front USB ports connected via one of the headers? Is it true for both USB 2 and 3 ports?
It's possible that a bad component is shorting a signal on your board.
To troubleshoot:
The goal is to isolate the source of potential problems. You have to do it systematically. Rushing will make the troubleshooting worthless. Take notes.
When you have a moment, a list of the system hardware would be helpful. Also if you have the paper manual for the motherboard get it out.