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tl;dr: we don't know yet.
If I had to guess, I'd say microplastics or some dietary thing like aspartame.
But there's also a link between colon cancer and running. The article mentions two people as pictures of health who run a lot.
Pictures of health could still be drinking PFOA and other crap if their drinking water hasn’t been tested.
Kidney and Colon cancer are two of the most linked diseases to if.
I always knew running was bad news. 😏
We don't know yet, but the article mentions it's likely that the gut microbiome is involved, which means microplastics and food additives are unlikely to have much of an importance.
There are plenty of pathogens that cause cancers, and the article implies something about our lifestyle or their own evolution has turned a formerly benign entity against us.
My bet's on Long COVID. It's been connected to so many other random medical issues popping up (including diabetes, low sperm counts, and early onset Alzheimers IIRC) that it may as well be connected to ass cancer as well.
Hadn't heard or thought about that, but it is an intriguing hypothesis!
I would assume food additives impact the gut biome, a casual search suggests as much. I wouldn't rule out plastics either, though they are clearly more of an unknown.
I know alot of people get into running to cope with stress. Maybe that is a possibile link.
I've heard about that link before
https://www.inovanewsroom.org/press-release/2025/08/groundbreaking-inova-study-finds-potential-link-between-long-distance-running-and-colon-cancer/
Most synthetic sweeteners are considered scientifically rigorously tested and safe for consumption. :)
Same with glyphosate, I drink that shit every day and no weeds coming out my ass!