Transfem
A community for transfeminine people and experiences.
This is a supportive community for all transfeminine or questioning people. Anyone is welcome to participate in this community but disrupting the safety of this space for trans feminine people is unacceptable and will result in moderator action.
Debate surrounding transgender rights or acceptance will result in an immediate ban.
- Please follow the rules of the lemmy.blahaj.zone instance.
- Bigotry of any kind will not be tolerated.
- Gatekeeping will not be tolerated.
- Please be kind and respectful to all.
- Please tag NSFW topics.
- No NSFW image posts.
- Please provide content warnings where appropriate.
- Please do not repost bigoted content here.
This community is supportive of DIY HRT. Unsolicited medical advice or caution being given to people on DIY will result in moderator action.
Posters may express that they are looking for responses and support from groups with certain experiences (eg. trans people, trans people with supportive parents, trans parents.). Please respect those requests and be mindful that your experience may differ from others here.
Some helpful links:
- The Gender Dysphoria Bible // In depth explanation of the different types of gender dysphoria.
- Trans Voice Help // A community here on blahaj.zone for voice training.
- LGBTQ+ Healthcare Directory // A directory of LGBTQ+ accepting Healthcare providers.
- Trans Resistance Network // A US-based mutual aid organization to help trans people facing state violence and legal discrimination.
- TLDEF's Trans Health Project // Advice about insurance claims for gender affirming healthcare and procedures.
- TransLifeLine's ID change Library // A comprehensive guide to changing your name on any US legal document.
Support Hotlines:
- The Trevor Project // Web chat, phone call, and text message LGBTQ+ support hotline.
- TransLifeLine // A US/Canada LGBTQ+ phone support hotline service. The US line has Spanish support.
- LGBT Youthline.ca // A Canadian LGBT hotline support service with phone call and web chat support. (4pm - 9:30pm EST)
- 988lifeline // A US only Crisis hotline with phone call, text and web chat support. Dedicated staff for LGBTQIA+ youth 24/7 on phone service, 3pm to 2am EST for text and web chat.
view the rest of the comments
one potential problem you would likely run into is spiky estrogen blood levels - oral and rectal administration is not ideal for this reason, and is a reason to use routes like injections, patches, or gel.
You ideally want gradual increases and decreases to blood estrogen levels, for so many reasons.
But yes, I think theoretically you will have better absorption from rectal administration because you bypass the liver.
But again this will cause huge and short-lived spikes in blood estrogen making it a terrible idea. Again, the best solution is to change your route of administration to injections, patches, or gel.
There are rectal and vaginal estrogen suppositories that are actually dosed and manufactured for this purpose, I would guess they would have lower doses because of the better absorption. They might be dosed much lower since usually they are supplementation for peri and post menospausal cis women who still produce some endogenous estrogen.
edit: was reading 1 mg estradiol taken rectally will send blood levels over 600 pg/mL at peak and peak is within 3 hours, this sounds like a bad time to me, and I assume oral pills are usually more than 1 mg ...
even my estradiol valerate injections that peak in 1 - 3 days feel too spikey and can create mood swings, and esters like cypionate and enenthate which have much longer half lives feel smoother and more mood-stable when taken at the right dose, frequency, and route of administration.
You will also have better feminization from consistent blood estrogen levels with less spikey methods, whereas spikey oral and rectal administration will leave you without consistently sufficient blood estrogen levels through the day and especially at night when you aren't likely to wake up to dose when you would need to.