this post was submitted on 22 Sep 2025
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Tylenol would be a prescription drug if it hit the market today. Had a friend blow her liver and lie in a coma for two months until she got a transplant. She was a hardcore alcoholic, and this is an alcoholic saying that. Doctor addressed the family and told them alcohol wasn't the factor, the liver failure was 100% down to Tylenol.
OTOH, I've seen a lot of ignorant comments from people thinking it does cumulative damage. Nope, just don't do too much at once.
That doesn't sound realistic, that a hardcore alcoholic's liver failure was 0% from alcohol abuse. I suspect that the information changed at some point in the process of relating it to you.
It was probably just that the Tylenol overdose was the immediate cause, and somebody took that to mean that alcoholism was not a factor.
Probably that paracetamol becomes far more toxic when alcohol has depleted the liver's glutathione stores
She was popping them like Tic Tacs. When they dropped the new liver in, they found 3' of gangrenous small intestine, hence the overdose. She'd pop two, still in pain, no difference, pop another two, rinse and repeat, all afternoon.
Can't remember what she estimated, won't try to repeat it, but she went fucking nuts. I think that would kill about any of us.
Glad we have these conversations. We were all shocked to learn that Tylenol could crash your liver. Wasn't the common knowledge 25-years ago that it is today.
Surgeon said her alcoholism was hardly a factor. "Believe it or not...", were his words. He saw her fucking liver, in situ, I'm going to go with his expertise.
Given that she was only around 40, and given that some of us have "Ozzy" genes, I'm not too surprised, though I was at the time. Human's can have wildly different experiences, no one-size-fits-all. Hell, I'm not allergic to poison ivy. Weird.
Ah, of course. When, as you said, the doctor addressed "the family" and told "them" that stuff, of course, I assumed that you, being "a friend" wouldn't have been there, or at least would have said "us" instead of "them."
But of course, you were actually there and heard the words directly with the family. Cool.