Ask Science
Ask a science question, get a science answer.
Community Rules
Rule 1: Be respectful and inclusive.
Treat others with respect, and maintain a positive atmosphere.
Rule 2: No harassment, hate speech, bigotry, or trolling.
Avoid any form of harassment, hate speech, bigotry, or offensive behavior.
Rule 3: Engage in constructive discussions.
Contribute to meaningful and constructive discussions that enhance scientific understanding.
Rule 4: No AI-generated answers.
Strictly prohibit the use of AI-generated answers. Providing answers generated by AI systems is not allowed and may result in a ban.
Rule 5: Follow guidelines and moderators' instructions.
Adhere to community guidelines and comply with instructions given by moderators.
Rule 6: Use appropriate language and tone.
Communicate using suitable language and maintain a professional and respectful tone.
Rule 7: Report violations.
Report any violations of the community rules to the moderators for appropriate action.
Rule 8: Foster a continuous learning environment.
Encourage a continuous learning environment where members can share knowledge and engage in scientific discussions.
Rule 9: Source required for answers.
Provide credible sources for answers. Failure to include a source may result in the removal of the answer to ensure information reliability.
By adhering to these rules, we create a welcoming and informative environment where science-related questions receive accurate and credible answers. Thank you for your cooperation in making the Ask Science community a valuable resource for scientific knowledge.
We retain the discretion to modify the rules as we deem necessary.
view the rest of the comments
3mg per kilogram of mass apparently
https://www.nature.com/articles/s41598-024-52599-y
Though in reality you probably want to chat with your doctor if you're shooting for that.
That's approximately 1.5 to 2 cups of coffee an hour for me
You might want to look up "half life of caffeine" before you spend all day drinking like that. Your body metabolizes caffeine differently than alcohol.
Alcohol is linier e.g. 1oz/hr. Caffeine is halfed every ~5 hours. So if you start at 100mg, 5 hours later you're going to have 50mg still going, 10 hours down the road you have 25mg. Fun times if you have 4 cups of coffee over a two hour period at 90mg a cup you're going to have ~350mg and it's going to take ~20 hours to get under 25mg.
There are numerous apps to track the actual amount of caffeine in your system at any given time and you might be surprised at how high the numbers go if you haven't tracked it before.
Great point about half-life, but there's also huge genetic variation - some people with CYP1A2 gene variants metabolize caffeine up to 4x faster than others, which is why some can have an espresso before bed while others get jittery from a small cup in the morning.
I think your physical activity have an influence on the metabolizing of coffeine.
Source: me. I have noticed a late coffee will more likely mess my sleep if I did not move my ass in the afternoon. Might also simply be the lack of physical activity though.
~~Yeah I took into account a 5h half life, I'm a tall guy haha~~
Well I did, but messed up something else. It's more like a coffee every 2h or so for me
3mg/kg for me is about 350mg, so if I've not messed up the maths a 2nd time, I'd need to smash 4 coffees in the morning to get up to that level and then one every 2h30 to sustain
This is just a paper on the effect of 3mg/kg on esports skills, it's literally the first sentence of the abstract. It has nothing to do with finding an optimal dose.
Oh sorry, I thought it came across in my delivery I wasn't being serious that people should do this
Heh I missed that you said "per hour" at the end, not per day. I should have caught that.