this post was submitted on 01 Aug 2025
734 points (99.5% liked)

Comic Strips

18495 readers
2567 users here now

Comic Strips is a community for those who love comic stories.

The rules are simple:

Web of links

founded 2 years ago
MODERATORS
you are viewing a single comment's thread
view the rest of the comments
[–] ArbitraryValue@sh.itjust.works 4 points 1 day ago* (last edited 1 day ago)

I actually failed my molecular biology course, and I'm still a little salty about that. I understood molecular biology. I didn't memorize stuff like the order in which subunits bind to assemble the pre-replication complex.

After ORC1-6 bind the origin of replication, Cdc6 is recruited. Cdc6 recruits the licensing factor Cdt1 and MCM2-7. Cdt1 binding and ATP hydrolysis by the ORC and Cdc6 load MCM2-7 onto DNA.

Note that they're numbered but the numbers aren't related to the order in which they act. I don't need to know that. No one who doesn't do research specifically on the pre-replication complex needs to know that.

(Excuses, excuses...)