Scientifically, I think (based on all the huberman ep's I've listened to) it's cuz it makes up for our lack of dopamine receptors helping us perform tasks, and our minds act like a NT's, and since an NT's dopamine levels are normal it sends them into overdrive and makes them hella overstimulated.

Dats why when NT's take addy recreationally it makes them go mental, cuz it's basically a controlled version of speed. I don't do blow but I know certain man with ADHD who have and they tell me it knocks them out, like a sleeping pill.

[–] Nefara@lemmy.world 16 points 3 months ago (2 children)

My understanding is that the ADHD brain activity resembles an NT's when they're extremely tired or sleep deprived, with a lot of theta wave activity. Stimulants can help jog an ADHD person's brain into alpha and beta waves, which are associated with relaxation or alertness and focus.

[–] rhombus@sh.itjust.works 3 points 3 months ago (1 children)

It’s a bit of both with a healthy dose of “we’re not sure”. We know that ADHD brains don’t regulate neurotransmitters properly and that the theta vs beta waves are different, but there are a lot of other mechanisms we don’t understand.

Another great example is guanfacine. It’s primarily a blood pressure medication, but it also improves emotional regulation for ADHD patients. We think it improves connections in the prefrontal cortex, but we ultimately don’t have a solid understanding of why it actually helps.

[–] MutilationWave@lemmy.dbzer0.com 1 points 3 months ago* (last edited 3 months ago)

I started taking guanfacine because I'm at Adderall max, which is way too low. I have been taking it for a over a month and I can't feel any difference.

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